Pharmaceutical Assay and Quality Control Testing with Volumetric Flasks
Accuracy as the Foundation of Pharmaceutical Testing The quality control of pharmaceuticals relies on analytical measurements that are accurate, precise, reproducible and fit to their use. Whether the laboratory is identifying assay or potency, assessing impurities, performing stability testing or assessing raw materials, the outcome of analysis is not only reliant upon the tool and validated procedure, but also upon the preparation of solutions prior to measurement. Routine preparation of reference standard solutions, sample solutions, calibration solutions, intermediate dilutions and reagents are done in pharmaceutical laboratories. In both instances, the solution volume can be directly affected by the amount of material, and hence the concentration calculated. A mistake in weighing, in transfer or in adjusting volume may thus be included in the analytical result. Volumetric Flasks are intended to be used in the preparation of solutions of a certain volume under specific calibration...